Adenovirus-Mediated Gene Expression In Vivo Is Enhanced by the Antiapoptotic Bcl-2 Gene
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چکیده
منابع مشابه
Modeling gene expression in the mouse uterine horn by in vivo adenovirus-mediated gene delivery.
Endometrium is a unique tissue that is prepared for implantation of blastocyst during each menstrual cycle by expression of genes during a defined period of endometrial receptivity. Induction of gene over-expression in endometrium allows gaining insight on the role that genes play in endometrial function. Here, we show that induction of a state of gene over-expression in endometrium is feasible...
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To regulate expression of a transferred gene in response to an exogenous compound, we have combined a high capacity adenoviral vector devoid of all viral coding sequences with a regulatory system that can be used to express a target gene in vivo in a selected site and at a desired time. This system uses a chimeric transactivator, GLp65, which consists of a mutated progesterone receptor-ligand b...
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ژورنال
عنوان ژورنال: Journal of Virology
سال: 1999
ISSN: 0022-538X,1098-5514
DOI: 10.1128/jvi.73.8.6992-7000.1999